NUCLEAR NEUROLOGY Hypofrontality and Negative Symptoms in Major Depressive Disorder

نویسندگان

  • Igor I. Galynker
  • Jun Cai
  • Fukiat Ongseng
  • Howard Finestone
  • Eamon Dutta
  • Dragos Serseni
چکیده

The purpose of the current study was to compare regional cerebral blood flow (rCBF) in patients with major depressive disorder (MOD) to that of healthy subjects and to examine the relationship between rCBF, depressive symptoms (DS) and negative symptoms (NS) in these patients. Methods: Eleven psychiatric inpatients with diag nosed (MOD) and 15 normal control subjects were administered the scale for the assessment of negative symptoms (SANS) and the modified Hamilton rating scale for depression with items descriptive of NS excluded (HRSD-DS). Each patient underwent a SPECT scan using ""Tc-HMPAO at rest. Cortical and subcortical regions of

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Hypofrontality and negative symptoms in major depressive disorder.

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تاریخ انتشار 2006